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Category Archives: Ihalation therapy

Disscusion of Aerosol Penetration

We found that low therapeutic concentrations of theophylline significantly increased aerosol penetration in the lung of healthy subjects based on the finding of significantly lower mean skew with theophylline. Neither mucociliary clearance nor tracheal mucociliary transport rate was different between …

Aerosol Delivery Systems

Delivery of aerosolized bronchodilator agents through metered-dose inhalers (MDI) has enjoyed wide popularity because these devices are portable and convenient, require minimum time for administration, and have the potential for effecting rapid relief of bronchospasm. More recently, it has been …

Aerosol Deposition in Inhalation Therapy

When the above considerations are taken into account, it seems that for aerosol therapy we require as ideals: (1) aerosol MMAD <5 to minimize oropharyngeal deposition, (2) slow, steady inhalation, and (3) a period of breath-holding on completion of inhalation. …

Aerosol Deposition

The ihalation therapy has several well-established advantages over the oral and intravenous (IV) routes: (1) A small dose of drug can be used; a few hundred micrograms of inhaled (3-agonist may be as effective as a 10-mg oral dose. (2) …

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