Category Archives: Increased in smokers

Although we did not measure carboxy-hemoglobin in the smokers in this study, most of whom reported smoking in the 2 h before testing, it would likely have been elevated, accounting for most of the apparent reduction in DLcoSb-3EQ measured from …

Previous reports found that the conventional single breath diffusing capacity for carbon monoxide (DLcoSb) was reduced in smokers and correlated with macroscopic disease, as detected by CT scan techniques . However, in seated patients at rest DLcoSb was insensitive to …

Abnormalities in the phase III nitrogen slope in a group of healthy smokers with otherwise normal lung function have been previously reported for SBWvc, but only when the smokers forcibly exhaled to Rv immediately before performing the SBWvc manoeuvre . …

Two possible mechanisms could explain this observation. First, the decrease in Di and the shallower Sn with breath holding for SBWSM may both be explained by the common effect of small airway inflammation and/or regional loss of elastic recoil on …

Smoking produces a number of pathological lesions in the lung . Recent observations using computed tomography (CT) revealed surprisingly common abnormalities in smokers with relatively normal lung function. The abnormalities consisted of ground glass attenuation, micronodules and diffuse emphysematous changes …

The most remarkable finding in this study was that Di was significantly higher in smokers for SBWSM at 0 s of breath holding and correlated with cumulative pack-years of smoking. The fact that, for these manoeuvres, Di correlated with both …

SBWvc: DLcosb-3EQ measured from the whole sample was slightly lower in smokers (Table 1). DI was significantly increased in smokers (Table 1; P<0.05) and correlated with age in smokers (r =0.48; P<0.001) but not in nonsmokers, and with pack-years of …

Effect of 10 s of breath holding on SBWsm: DLcoSb-3EQ from the total alveolar gas sample was similar between smokers and nonsmokers (Table 1). For DLcoSb-3EQ measured from small alveolar gas samples there was markedly less deviation of all four …

The characteristics of the smoking and nonsmoking groups, which have been previously reported , were similar in terms of sex distribution (smokers: 12 women and nine men; nonsmokers: 10 women and 11 men), age (smokers 39±8 years; nonsmokers 38±7 years, …

Di described the degree to which the four DLcoSb-3EQ values measured from the four alveolar gas samples deviated from the single DLcoSb-3EQ value measured from the entire alveolar gas sample by calculating the root-mean-square difference of the normalized DLcoSb-3EQ values …