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Category Archives: Meal-induced oxygen

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease: DISCUSSION (4)

We also found that dyspnea increased with eating and was greater during AE than PE. The finding of similar changes in dyspnea with eating in our subjects when grouped according to severity is not surprising because perceived breathlessness varies considerably …

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease: DISCUSSION (3)

We and others have noted that desaturation occurs relatively soon after the onset of eating . This mitigates against explaining the changes on the basis of the metabolic effects of food, changes that would require time for digestion and absorption. …

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease: DISCUSSION (2)

Moreover, meal-related desaturation tended to be more severe in those least able to tolerate such a change, ie, these with a lower baseline SpO2. This contrasts with the present study where we found no difference in the magnitude of meal-related …

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease: DISCUSSION (1)

In this study, we found a small but statistically significant decrease in oxygen saturation during both AE and PE in patients with COPD. Meal-induced desaturation was statistically greater during AE than PE, but the difference was small in absolute terms. …

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease: RESULTS (2)

For both groups, mean values for all three oxygen parameters measured changed significantly between control and eating periods during both AE and PE (P<0.001). Although mean SpO2 and mean lowest SpO2 were lower and percentage of time with SpO2 less …

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease: RESULTS (1)

As outlined above, premeal control saturation was always recorded during a standardized 20 min period. The mean duration of AE and PE during which oxygen variables were recorded was 18.0±3.8 and 18.4±4.2 mins, respectively. Table 2 shows the changes in …

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease: PATIENTS AND METHODS (3)

Because mean values during sustained activity may not adequately reflect periods of desaturation, two additional determinations were made. The lowest saturation recorded during pre-eating and eating phases was recorded for each subject, and mean values once again obtained for each …

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease: PATIENTS AND METHODS (2)

Eating studies: Eating studies were conducted during either the noon or evening meal. Meals were standard hospital fare with no attempt made to control for nutritional or caloric content. Patients were studied on two consecutive days, with active eating (AE) …

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease: PATIENTS AND METHODS (1)

Patients: Thirty-five patients with severe COPD were studied (Table 1). All subjects were former cigarette smokers with a clinical history consistent with COPD; patients were eligible for inclusion if they had a forced expiratory volume in 1 s (FEV1) less …

Meal-induced oxygen desaturation and dyspnea in chronic obstructive pulmonary disease

Patients with chronic obstructive pulmonary disease (COPD) often complain of dyspnea and may experience oxygen desaturation with activities of daily living . Eating is an activity common to all individuals. Although modest degrees of desaturation have been shown to occur …

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