Materials and Methods Patients Forty patients (31 male), with a mean age of 42.5 ±20.3 years, were studied. Seventeen were alcoholics, 14 were heavy smokers, and 8 patients had COPD. Other underlying diseases included three cases of diabetes mellitus, and one each of the following: chronic renal failure, asthma, breast cancer, rheumatoid arthritis, hepatic cirrhosis,…
The etiologic diagnosis of community-acquired pneumonia (CAP) is still a common medical problem. Streptococcus pneumoniae remains the most frequent cause of CAP, accounting for at least half of the cases. Increasing numbers of other organisms have been reported to be involved in the pathogenesis of this disease. Unfortunately, predicting the bacteria responsible for CAP based…
Logic would then dictate that groups at high risk for tuberculosis should be targeted for screening efforts. The estimated 24.4 percent prevalence of tuberculin reactors among our study population is about five times higher than the prevalence among the whole United States population, substantiating that our patient population is at high risk for tuberculosis and…
Although this is less than optimum, it must be remembered that this is a population that is in danger of receiving no screening at all. This method results in considerable cost savings and uses the nursing staffs limited time more efficiently than if chest roentgenograms alone are used on all patients, yet it yields more…
Our methods could potentially generate false-positive results in two ways. The first is that by reading the TBN-ST before 48 h, we could erroneously interpret a reaction not due to delayed hypersensitivity as a positive reading. Immediate hypersensitivity reactions to PPD occur in approximately 2 percent of people who receive PPD and resolve by 2…
Discussion Since the early 1930s, it has been recommended that a TBN-ST be read at no earlier than 48 h. However, this was not always the case. In one of his initial reports, Mantoux stated that a positive tuberculin reaction is apparent by 24 h. Despite this, it became clear in subsequent years that although…
The two estimates of the true prevalence of reactors in our study population, 23.1 percent and 25.7 percent, are in close agreement. Averaging the two, 24.4 percent is the final estimated prevalence of true tuberculin reactors in our study population. Using this number, we can estimate the sensitivity of our method for both the whole…
1. Seventy patients had only a 48- to 72-h reading of their skin test. Of these, 18 were positive and 52 were negative, yielding a prevalence of true-positive tuberculin reactors of 25.7 percent. If this percentage is extrapolated to the whole study population, then 25.7 percent of 1,412 or 362 patients would have had positive…
Follow-up There were 272 women referred to the San Diego County Tuberculosis Control office because of a positive chest roentgenogram or a positive TBN-ST or a history of one. Only 39 called to make an initial appointment, 32 of whom had charts available for review. All but two of these women were lost to follow-up…
Seventy-six patients were excluded from the study because the study protocol had not been followed up. One additional patient had an initial reading at 16 h of 18 mm of induration, while the patient had a 48-h reading of 0 mm of induration. A chest roentgenogram, however, showed changes consistent with prior tuberculosis. Because we…
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