Notably, this study was not conducted in a double-blind fashion and the induration was quantified by different readers. The authors suggested that the results from the pen technique must be interpreted with caution in that range. Our results comparing the two methods in a “double-blind” fashion indicate that the pen method is comparable to the…
The standard tuberculin skin test which, if positive, is taken as the definition of tuberculous infection is the Mantoux test.2One of its disadvantages over multiple puncture tests is that it must be performed and read by trained personnel. Clinical utilization of the Mantoux test is hampered by the difficulty and variability in quantifying the resultant…
Of the 40 subjects who had an induration of 1 to 4 mm measured by the palpation method, two had an induration ^10 mm and three between 5 to 9 mm. The statistical analysis of these 40 measurements made by the two methods showed no statistically significant difference (p>0.1), (Table 1, 2nd column). Similarly, the…
The frequency distributions of induration measured by the two methods are shown in the histogram of Figure 1. The induration ranged from 0 to 26 mm for the palpation method and from 0 to 28 mm by the pen method. Of the total of 1,340 tuberculin skin tests, 1,095 by palpation and 1,093 by the…
The test was considered successful, if after injection of 0.1 ml of tuberculin, a wheal of at least 6 to 10 mm in diameter was produced. Necessary precautions were taken to avoid any bias due to quality, quantity, or method of administration. Skin tests were read after 48 hours by the same experienced pulmonologist. In…
The usual method of tuberculin skin reaction measurement of induration is palpation. Unfortunately, even skilled examiners may have considerable difficulty in identifying or measuring induration by this method. A 2 percent error in the measurement decreases the accuracy of the method by 25 percent, exceeding 50 percent for a 5 percent error. The measurement of…
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